TADORA® (Tadalafil 20 mg)

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Tadora, an oral drug based on tadalafil citrate (commercialized under the brand name of Cialis), is a popular generic of the “weekend pill.”


Tadora (tadalafil 20 mg) is an oral drug administered to men with a clinically diagnosed inability to achieve and / or maintain erection sufficient for engaging in sexual intercourse. The drug is taken 30 to 40 minutes prior to anticipated sexual activity, and acts during 36 hours after the onset.

Tadora is a generically produced drug. “Generic” is a term applied to drugs produced by manufacturers outside of the pool of original preparation holders. The composition of generic drugs is identical when it comes down to active components. In certain cases, generic and brand drugs may differ in their excipients (complementary substances used to give the product its pharmacological shape). Thus, Tadora features the same ingredients as the brand Cialis.

Tadora’s price is different from that of the original Cialis, and the rationale behind this price gap is the money invested in developing, testing, and promoting the brand medication by the original developer. Generic manufacturers skip all of these costs, and are therefore able to quote much lower prices.


The active substance tadalafil citrate contained in Tadora is a hypertensive agent. It acts as a dilator of blood vessels, which leads to maximal absorption of blood in the penile arteries. Since this mechanism is based on inhibition of the enzyme whose overproduction makes the walls of blood vessels stiff and inelastic, and the enzyme is called phosphodiesterase type 5, tadalafil and drugs of its class with similar action are referred to as PDE5 inhibitors in the literature.

Tadalafil is not an inducer of sexual desire; its health effects will be manifested only in presence of sufficient sexual stimulation. At the same time, one can speak of a certain degree of sexual enhancement, as Tadora improves sexual response due to its mechanism aimed at increased circulation in the genital area. Additionally, Tadora decreases refractory time (the amount of time required to recharge between sexual acts) and allows for several erections to take place within a shortened timeframe.

These are the basic facts one needs to understand about Tadora’s mechanism:

  • Tadora inhibits PDE5, promoting the release of nitric oxide (NO), which in its turn promotes the release of cyclic guanosine monophosphate (cGMP).
  • The balance of substances in the erectile bodies of the penis (the corpra cavernosa and the corpus spongiosum) favors elasticity of blood vessels and restores erectile function.
  • Tadora has no effect on sexual desire; it makes it possible to achieve erection as a result of sexual stimulation.


In clinical trials, the following side effects of tadalafil were registered in 15% of patients receiving 20 mg (a dose contained in Tadora):

  • headache
  • muscle pain
  • nausea
  • facial flushing
  • diarrhea
  • upset stomach
  • change in color perception
  • tingling in the ears
  • prolongated QT time

In case of the following adverse events, seek immediate medical help:

  • swelling of lips, tongue or face
  • skin rash
  • palpitations, irregular heart beat
  • abnormally long-lasting or painful erection
  • pain in the chest and/or arm

The list of tadalafil side effects is incomplete. Consult your healthcare specialist, pharmacy technician or manufacturer’s insert for full information.


Tadora 20 mg is intended to be taken on demand. It means that a tablet is taken prior to sexual activity, allowing for the time required for tadalafil effect to set in—approximately 30-40 minutes.

Wash down a pill of Tadora with a ½-1 glass of water. Avoid drinking grapefruit juice or eating the fruit itself; the enzyme CYP 3A4 that metabolizes it is also engaged into metabolization of tadalafil. Concomitant use of both substances can lead to increased toxicity of the drug. For the same reason, the use of Tadora should be cautioned against in individuals with compromised renal or liver function. Do not take more than 1 tablet of Tadora during a 24-hour period. The drug can be taken with or without meals; timing the intake of Tadora with food intake will decrease the risk of adverse events.


The effects of Tadora last within the ensuing 36 hours after the onset of tadalafil action. During this time, the user will experience the following benefits:

  • restored erectile mechanism
  • increased erectile hardness
  • absence of performance-related anxiety
  • improved control over ejaculation
  • heightened sensitivity of penile tissues
  • shortened refractory periods


According to the original manufacturer, tadalafil can be coadministered with alcohol as the latter does not affect the drug’s efficiency. User’s discretion is required though: alcohol is a stopping substance that compromises bodily functions, including sexual function, so while the effects of Tadora will remain uninhibited, general sexual performance will be decreased.


The following table represents the difference between the basic phacacodynamics of Tadora (tadalafil citrate) and Viagra (sildenafil citrate).

SubstancePharmacological formOnset timeDuration of actionCompatibility with alcohol
SildenafilFilm-coated tabletsMax. 60 min4-6 hoursPoor
TadalafilFilm-coated tabletsMax 40 min36 hoursExcellent


“I have had diabetes for more than 6 years. Tadora is the only substance that can help me get it up… I take one pill before bedtime, and it lasts me till the morning of the day after. I feel like a healthy person getting morning erections and spontaneous erections as I used to back in my 20s. The price is the drug’s major advantage!”

Luis, 47

“I have to take something for my potency in order to counter the effects of antidepressants I am on. So far, so good. With Tadora, I feel the effects within an hour of taking, and I totally forget about erectile difficulty for a couple of days after that.”

Calvin, 27

“Tadora is my lifeline. I used to experience nasty side effects like upset stomach and flu-like symptoms with other generic tadalafil drugs. Tadora is the first pill that has a clockwork efficacy and doesn’t make me choose between general wellbeing and my erectile function!”

Brandon, 63

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